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Medical Assistant Salaries in Missouri — 2026 Overview

BLS 2026

The median medical assistant salary in Missouri is $39,310 per year, equivalent to $18.90/hr, based on the Bureau of Labor Statistics OEWS programme. Missouri employs approximately 11,860 medical assistants statewide.

Medical Assistant salaries in Missouri are below the national average by approximately $3,723. Missouri has a state income tax rate of up to 4.8%.

A solid industrial economy and stable population mean medical assistants in Missouri enjoy reliable job security.

Missouri Medical Assistant Take-Home Pay Calculator

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Enter your gross annual salary to estimate take-home pay in Missouri after federal tax, Social Security and Medicare. Missouri has a state income tax rate of up to 4.8%.

Your annual gross salary ($)
Gross Annual
$39,310
Federal Tax (est.)
calculating...
FICA + State Tax
calculating...
Estimated Take-Home
$32,770

Estimate based on 2026 federal tax brackets, single filer, standard deduction. Missouri has a state income tax rate of up to 4.8%. Does not account for local taxes or benefit deductions.

Am I Paid Fairly? — Missouri Medical Assistant Check

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Enter your current salary to see how it compares to the Missouri median of $39,310.

Your annual salary ($)

Medical Assistant Salary by Experience — Missouri

Entry Level (0–2 years)$24,400/yr · $11.73/hr
Beginning career, developing core skills under supervision in Missouri.
Mid-Level (3–6 years)$34,985/yr · $16.82/hr
Established professional working independently in Missouri. Pursuing advanced certifications.
Experienced (7–12 years)$43,634/yr · $20.98/hr
Senior professional with specialised skills commanding above-average pay in Missouri.
Senior / Expert (12+ years)$56,600+/yr · $27.21/hr
Top earner. Leadership, management or highly specialised role in Missouri.
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Medical Assistant Salary Trend in Missouri — 2021 to 2026

5-Year Data

Five-year wage growth for medical assistants in Missouri: 13.9% — a useful benchmark when negotiating pay or planning a career move. The growth reflects broader workforce and economic conditions in Missouri's healthcare and physician offices.

2021
$34,514
2022
$36,518
+5.8%
2023
$38,209
+4.6%
2024
$38,838
+1.6%
2026
$39,310
+1.2%

Medical Assistant Salary by City — Missouri

BLS Metro Data
City / Metro AreaAnnual MedianHourlyvs StateJobs
Kansas City$43,650$20.99+11.0%4,151
Saint Louis$41,650$20.02+6.0%3,320
Springfield$40,500$19.47+3.0%2,134
Columbia$37,750$18.15-4.0%1,067
Independence$35,750$17.19-9.1%711
Jefferson City$34,200$16.44-13.0%474

Tip: Kansas City offers the highest medical assistant salaries in Missouri at $43,650/yr — +11.0% above the state average.

Missouri vs Nearby States — Purchasing Power

Cost of Living Adjusted

Gross salary figures don't tell the whole story. After adjusting for state income tax, Missouri sits in the mid-range for medical assistants.

Missouri — 4.8% state income tax$39,310 gross~$32,770 take-home
Iowa — 6.0%$43,670 gross+11.1% vs MO
Illinois — 4.95%$45,490 gross+15.7% vs MO
Kentucky — 4.0%$38,750 gross-1.4% vs MO

Take-home estimates based on single filer, standard deduction, 2026 federal brackets. Missouri has a state income tax rate of up to 4.8%.

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Medical Assistant Job Outlook in Missouri

BLS Projections
+10%Job growth 2026–33
11,860Currently employed
1,186+New jobs projected

Employment for medical assistants in Missouri is projected to grow over the next decade, driven by strong demand across the Missouri job market. A solid industrial economy and stable population mean medical assistants in Missouri enjoy reliable job security.

How to Earn More as a Medical Assistant in Missouri

1. Pursue advanced certification or licensing. Moving from entry to senior level as a medical assistant in Missouri typically adds $32,200 to your annual salary. Additional certifications from the State Medical Board can accelerate this progression.

2. Target the highest-paying city. Kansas City pays medical assistants $43,650/yr — +11.0% above the Missouri average. Simply relocating within Missouri can meaningfully increase your income without changing careers.

3. Specialise in high-demand areas. Medical Assistants who specialise in healthcare and physician offices typically command premium rates in Missouri. Identifying growing niches within your field is one of the fastest paths to higher pay.

4. Consider neighbouring states. Iowa pays medical assistants $43,670/yr — 11.1% vs Missouri.

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Frequently Asked Questions

How much do medical assistants earn in Missouri?
The average medical assistant salary in Missouri is $39,310 per year, or $18.90 per hour, based on the latest Bureau of Labor Statistics OEWS data (2026 update). Entry-level positions start around $24,400 while experienced professionals earn $56,600 or more.
Which Missouri city has the highest medical assistant salary?
Kansas City pays medical assistants the most in Missouri at an average of $43,650 per year — +11.0% above the state average.
How does Missouri medical assistant salary compare to the national average?
Missouri medical assistant salaries are below the calculated national average by approximately $3,723. Missouri has a state income tax rate of up to 4.8%.
What is the take-home pay for a medical assistant in Missouri?
A medical assistant earning the Missouri average of $39,310 takes home approximately $32,770 per year after federal income tax, Social Security and Medicare. Missouri has a state income tax rate of up to 4.8%.
Is medical assistant a good career in Missouri?
Yes. Medical Assistant is a strong career choice in Missouri with steady demand projected over the next decade. A solid industrial economy and stable population mean medical assistants in Missouri enjoy reliable job security.
How do you become a licensed medical assistant in Missouri?
In Missouri, medical assistants are licensed through the State Medical Board. Requirements vary by specialisation level — contact the State Medical Board for current examination and experience requirements.
DATA SOURCE All salary data from Bureau of Labor Statistics OEWS May 2024 survey. Employment projections from BLS Occupational Outlook Handbook. Full methodology →

Important disclaimer: Salary and wage data on WageByState is provided for informational purposes only. Figures are sourced from the Bureau of Labor Statistics OEWS programme and represent median values across large populations — your individual earnings will vary. Take-home pay calculations are estimates and do not constitute tax advice. WageByState accepts no liability for decisions made based on information on this site. Not affiliated with the Bureau of Labor Statistics or any government agency.