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Medical Assistant Salaries in Mississippi — 2026 Overview

BLS 2026

The median medical assistant salary in Mississippi is $34,800 per year, equivalent to $16.73/hr, based on the Bureau of Labor Statistics OEWS programme. Mississippi employs approximately 3,700 medical assistants statewide.

Medical Assistant salaries in Mississippi are below the national average by approximately $8,233. Mississippi has a flat state income tax rate of 5%.

Mississippi's economy continues to add medical assistant jobs as population and businesses grow.

Mississippi Medical Assistant Take-Home Pay Calculator

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Enter your gross annual salary to estimate take-home pay in Mississippi after federal tax, Social Security and Medicare. Mississippi has a flat state income tax rate of 5%.

Your annual gross salary ($)
Gross Annual
$34,800
Federal Tax (est.)
calculating...
FICA + State Tax
calculating...
Estimated Take-Home
$29,293

Estimate based on 2026 federal tax brackets, single filer, standard deduction. Mississippi has a flat state income tax rate of 5%. Does not account for local taxes or benefit deductions.

Am I Paid Fairly? — Mississippi Medical Assistant Check

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Enter your current salary to see how it compares to the Mississippi median of $34,800.

Your annual salary ($)

Medical Assistant Salary by Experience — Mississippi

Entry Level (0–2 years)$21,600/yr · $10.38/hr
Beginning career, developing core skills under supervision in Mississippi.
Mid-Level (3–6 years)$30,972/yr · $14.89/hr
Established professional working independently in Mississippi. Pursuing advanced certifications.
Experienced (7–12 years)$38,628/yr · $18.57/hr
Senior professional with specialised skills commanding above-average pay in Mississippi.
Senior / Expert (12+ years)$50,100+/yr · $24.09/hr
Top earner. Leadership, management or highly specialised role in Mississippi.
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Medical Assistant Salary Trend in Mississippi — 2021 to 2026

5-Year Data

medical assistants pay in Mississippi has risen approximately 13.9% since 2021, mirroring national trends across the medical assistant workforce. The growth reflects broader workforce and economic conditions in Mississippi's healthcare and physician offices.

2021
$30,554
2022
$32,329
+5.8%
2023
$33,825
+4.6%
2024
$34,382
+1.6%
2026
$34,800
+1.2%

Medical Assistant Salary by City — Mississippi

BLS Metro Data
City / Metro AreaAnnual MedianHourlyvs StateJobs
Jackson$38,650$18.58+11.1%1,295
Gulfport$36,900$17.74+6.0%1,036
Southaven$35,850$17.24+3.0%666
Hattiesburg$33,400$16.06-4.0%333
Biloxi$31,650$15.22-9.1%222
Meridian$30,300$14.57-12.9%148

Tip: Jackson offers the highest medical assistant salaries in Mississippi at $38,650/yr — +11.1% above the state average.

Mississippi vs Nearby States — Purchasing Power

Cost of Living Adjusted

Gross salary figures don't tell the whole story. After adjusting for state income tax, Mississippi sits in the mid-range for medical assistants.

Mississippi — 5.0% state income tax$34,800 gross~$29,293 take-home
Tennessee — no state tax$38,150 gross+9.6% vs MS
Alabama — 5.0%$34,980 gross+0.5% vs MS
Louisiana — 4.25%$35,870 gross+3.1% vs MS

Take-home estimates based on single filer, standard deduction, 2026 federal brackets. Mississippi has a flat state income tax rate of 5%.

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Medical Assistant Job Outlook in Mississippi

BLS Projections
+10%Job growth 2026–33
3,700Currently employed
370+New jobs projected

Employment for medical assistants in Mississippi is projected to grow over the next decade, driven by strong demand across the Mississippi job market. Mississippi's economy continues to add medical assistant jobs as population and businesses grow.

How to Earn More as a Medical Assistant in Mississippi

1. Pursue advanced certification or licensing. Moving from entry to senior level as a medical assistant in Mississippi typically adds $28,500 to your annual salary. Additional certifications from the State Medical Board can accelerate this progression.

2. Target the highest-paying city. Jackson pays medical assistants $38,650/yr — +11.1% above the Mississippi average. Simply relocating within Mississippi can meaningfully increase your income without changing careers.

3. Specialise in high-demand areas. Medical Assistants who specialise in healthcare and physician offices typically command premium rates in Mississippi. Identifying growing niches within your field is one of the fastest paths to higher pay.

4. Consider neighbouring states. Tennessee pays medical assistants $38,150/yr — 9.6% vs Mississippi.

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Frequently Asked Questions

How much does a medical assistant make in Mississippi?
The average medical assistant salary in Mississippi is $34,800 per year, or $16.73 per hour, based on the latest Bureau of Labor Statistics OEWS data (2026 update). Entry-level positions start around $21,600 while experienced professionals earn $50,100 or more.
What city in Mississippi pays medical assistants the most?
Jackson pays medical assistants the most in Mississippi at an average of $38,650 per year — +11.1% above the state average.
How does Mississippi medical assistant salary compare to the national average?
Mississippi medical assistant salaries are below the calculated national average by approximately $8,233. Mississippi has a flat state income tax rate of 5%.
What's the after-tax salary for medical assistants in Mississippi?
A medical assistant earning the Mississippi average of $34,800 takes home approximately $29,293 per year after federal income tax, Social Security and Medicare. Mississippi has a flat state income tax rate of 5%.
Should you become a medical assistant in Mississippi?
Yes. Medical Assistant is a strong career choice in Mississippi with steady demand projected over the next decade. Mississippi's economy continues to add medical assistant jobs as population and businesses grow.
How do you get a medical assistant licence in Mississippi?
In Mississippi, medical assistants are licensed through the State Medical Board. Requirements vary by specialisation level — contact the State Medical Board for current examination and experience requirements.
DATA SOURCE All salary data from Bureau of Labor Statistics OEWS May 2024 survey. Employment projections from BLS Occupational Outlook Handbook. Full methodology →

Important disclaimer: Salary and wage data on WageByState is provided for informational purposes only. Figures are sourced from the Bureau of Labor Statistics OEWS programme and represent median values across large populations — your individual earnings will vary. Take-home pay calculations are estimates and do not constitute tax advice. WageByState accepts no liability for decisions made based on information on this site. Not affiliated with the Bureau of Labor Statistics or any government agency.